groei en lichaamssamenstelling body composition brain development
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Inclusion criteria
Inclusion criteria: Premature infants born before 30 weeks of gestation and admitted to the neonatal intensive care unit, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands
Exclusion criteria
Exclusion criteria: Severe congenital en/of chromosomal abnormalities Asfyxia (defined by cord blood or (if absent) first postnatal pH
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body composition measured by PEAPOD/BODPOD, defined by fat mass (FM, gram) and fat free mass (FFM, gram) using the BOD POD or DXA Neurodevelopment measured using Bayley Scales of Infant and Toddler Development, third edition (Bayley-III-NL), at 2 years corrected age and Wechsler Preschool and Primary Scale of Intelligence, third edition (WPPSI-III-NL), general intelligence assessment at 5.5 years corrected age and Wechsler Intelligence Scale For Children (WISC-V-NL), general intelligence assessment at 8 years corrected age. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Growth pattern - Nutritional intake (enteral and parenteral) - CUS measurements - Neurodevelopment at 2 years corrected age (Bayley-III motor score, Lexi-list and CBCL 1,5-5), 3 years corrected age (BRIEF-P and CBCL 1,5-5), 5,5 years corrected age (M-ABC-2, BRIEF-P and CBCL 1,5-5) and 8 years corrected age (M-ABC-2, BRIEF-2 and CBCL 6-18, TRF 6-18, OBVL). - Processing of visual stimuli (Eyetracker) - Sleep and circadian rhythm - Dental health status at 5.5 and 8 years corrected age - Bone mineral density at 3, 5,5 and 8 years corrected age - Parents* and patient reported quality of life (PedsQL and PROMIS 7+2) of preterm born children at 8 years corrected age. - Parents* needs in the neonatal follow-up program (qualitative research). | — |
Countries
Netherlands
Outcome results
None listed