Exploratory study regarding the use of Neurophysiological Monitoring Techniques to Detect Spinal Cord Ischemia in Patients after Thoracoabdominal Aortic Aneurysm Repair

Exploratory study regarding the use of Neurophysiological Monitoring Techniques to Detect Spinal Cord Ischemia in Patients after Thoracoabdominal Aortic Aneurysm Repair - Evaluating monitoring techniques for postoperative spinal cord ischemia

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52997

Enrollment

Registered

2016-10-12

Start date

2017-01-30

Completion date

Unknown

Last updated

2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myelum ischemia spinal cord damage

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age >= 18 years Thoraco-abdominal aneurysm (TAA) of the descending aorta: Crawford type I,II, III, IV or V Repair using open surgical or endovascular procedure. Undergoing monitoring by motor evoked potentials (MEP) as part of the standard surgical procedure.

Exclusion criteria

Exclusion criteria: Age

Design outcomes

Primary

Measure	Time frame
The study will consist of two parts. Part one refers to the intraoperative phase, the period when patients are fully sedated. This contains the whole period during surgery. Part two refers to the postoperative phase, the period after surgery when patients are fully sedated and when the level of sedation has been decreased and patients are only partially sedated and eventually awake. 1. During part one, the intraoperative phase, feasibility of the techniques described above will be determined and characteristics will be described. An association with the current gold standard (MEP signals) will be determined. 2. During part two, the postoperative phase, feasibility of the techniques described above will be determined and characteristics will be described. An association with hemodynamic characteristics as well as paraparesis at the end of the postoperative period (after the patient wakes up) will be determined.	—

Measure

Time frame

The study will consist of two parts. Part one refers to the *intraoperative phase*, the period when patients are fully sedated. This contains the whole period during surgery. Part two refers to the *postoperative phase*, the period after surgery when patients are fully sedated and when the level of sedation has been decreased and patients are only partially sedated and eventually awake. 1. During part one, the *intraoperative phase*, feasibility of the techniques described above will be determined and characteristics will be described. An association with the current gold standard (MEP signals) will be determined. 2. During part two, the *postoperative phase*, feasibility of the techniques described above will be determined and characteristics will be described. An association with hemodynamic characteristics as well as paraparesis at the end of the postoperative period (after the patient wakes up) will be determined.

—

Secondary

Measure	Time frame
As described in section above.	—

Countries

Netherlands

Outcome results