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The Influence of Vestibular and Muscle-Tendon Capacities on Locomotor Stability, Plasticity and Falls Incidence

The Influence of Vestibular and Muscle-Tendon Capacities on Locomotor Stability, Plasticity and Falls Incidence - Vestibular and Muscle-Tendon Influences on Locomotion

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON52987
Enrollment
60
Registered
2017-05-03
Start date
2017-05-30
Completion date
Unknown
Last updated
2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ageing and falls risk falls imbalance

Interventions

None listed

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Young healthy adults: • Between 20 and 30 years old • No known musculoskeletal disease, condition or injury that could negatively affect walking or balance ability • No history of balance problems, dizziness or walking difficulties • No participation in elite level competitive sports • Must be able to walk at a comfortable speed for 30 minutes without stopping • Informed consent given Older healthy adults: • Between 65 and 80 years old • No known musculoskeletal disease, condition or injury that could negatively affect walking or balance ability • No history of balance problems, dizziness or walking difficulties • Must be able to walk at a comfortable speed for 30 minutes without stopping • Informed consent given

Exclusion criteria

Exclusion criteria: • Not being able or willing to undergo the CAREN measurements following briefing and/or familiarization with the system and protocol • Incapacitated patients • Not being able to stop medication against anxiety or depression, if taken (after consulting their general practitioner) • Not wanting to be informed about any incidental findings (e.g. potential vestibulopathy detected in healthy subjects) • Is, or in the course of the study becomes, pregnant

Design outcomes

Primary

MeasureTime frame
The reactive adaptation potential measured during the locomotor plasticity assessment protocol with the CAREN will be the main parameter of the study. This will be calculated as the magnitude of change in the margin of stability at touchdown of the first step after the perturbation before and after repetition of the perturbation.

Secondary

MeasureTime frame
• Margins of stability, step width, length and cadence at touchdown of the first and following recovery steps after each perturbation • Various characteristics (e.g. local divergent exponent) of unperturbed walking at various speeds • For the young subject group: difference at each step and perturbation after 1 month (calculated as a percentage) in order to calculate locomotor retention • For the older group: falls incidence, type and cause of falls, and fear of falling from questionnaire data

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)