lung cancer non-small cell lung cancer
Conditions
Interventions
Usually mediastinoscopy will be performed first. Patients without metastatic
nodal spread will undergo subsequent anatomic resection of the primary tumour
and mediastinal lymph node dissection. The
Sponsors
Maxima Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with (suspected) NSCLC without distant metastases and suspected metastatic nodal spread on PET or CT scan; or a non PET-avid or centrally located tumour or a peripheral tumour >3 centimeters diameter. Previous EBUS/EUS has shown negative biopsy results.
Exclusion criteria
Exclusion criteria: Not eligible are patients with: a) highly suspected bulky mediastinal nodal disease; b) high suspicion of single level N2-3 metastasis defined by specific PET and EBUS/EUS characteristics; c) suspected non-resectable N2 disease; d) insufficient comprehension of the dutch language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary: unforeseen N2 rate. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary: a) health care utilization and costs; b) composite outcome of major morbidity plus 30-day mortality; c) overall and disease-free survival; d) disease-specific and generic quality of life. | — |
Countries
Netherlands
Outcome results
None listed