autoimmune disease Glutenintolerance
Conditions
Interventions
After informed consent the novel, validated, rapid point of contact (POC) tests
to determine coeliac-specific blood antibodies against the enzyme tissue
transglutaminase2 will be performed. If the P
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: age 12 months to 4 years, not diagnosed with CD, not on a GFD, one or more CD-associated symptoms are presented, parents have a sufficient knowledge of Dutch language, informed consent.
Exclusion criteria
Exclusion criteria: no informed consent, asymptomatic children, insufficient knowledge of Dutch language and/or inability to understand the information provided, children on a GFD children who are already diagnosed with CD
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Children already diagnosed with CD prior to the study (n) Time investment by medical and nursing staff at the YHCCs (sec) Costs of the investigational strategy (time, materials) (¤) Cost-effectiveness of the investigational strategy Acceptance of active case finding by the Dutch population | — |
Primary
| Measure | Time frame |
|---|---|
| Number of children with one or more CD-associated symptoms identified with CD at the YHCC by active case finding (n). Number of children with a positive POC test in which the diagnosis of CD is confirmed (n). | — |
Countries
Netherlands
Outcome results
None listed