Asthma bronchusobstruction
Conditions
Interventions
Intervention: a dietary advice of four unprocessed food products (NOVA 1or 2
classification foods)
300 ml full fat (3.4%) milk or yoghurt per day, 5 grams of butter per slice of
bread, about 100 grams of seasonal vegetables and 50-60 grams of beef. The
dietary intervention will be followed for 6
Sponsors
Ziekenhuisgroep Twente
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria are; - Children between 1 and 4 years old - Paediatric Asthma Score is 7 or above 7, with these scores there is a high chance of developing asthma (chance>25%).
Exclusion criteria
Exclusion criteria: -not understanding the Dutch language by the parents -a cow's milk protein allergy (or any other allergy to one of the components of the food intervention) at the time of the intervention. If patients never consumed cow*s milk proteins before, the risk of an allergy is unclear. In that case they cannot be included. If they have proven to tolerate cow*s milk protein in whatever form, they can be included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters/endpoints: a decrease in TRACK scores and LRSQ scores of the dietary intervention group compared to the control group. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are medication use, microbiome, immune analysis (cytokine profile, selective antibody production), IgA in saliva, adherence to the diet as well as growth parameters such as height, weight and Body Mass Index (BMI). | — |
Countries
Netherlands
Outcome results
None listed