Optimizing machine settings for contrast-enhanced ultrasound imaging of uterine disorders

Optimizing machine settings for contrast-enhanced ultrasound imaging of uterine disorders - CEUS imaging of uterine disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52905

Enrollment

Registered

2021-02-19

Start date

2022-05-30

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

adenomyosis growth of inner lining uterus into uterine wall

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - 18 years of age or older - abnormal uterine bleeding complaints - signed informed consent

Exclusion criteria

Exclusion criteria: - Woman with known allergy to SonoVue or any of its components - Severe heart disease or recent unset of rhythmic disorders - Pregant women

Design outcomes

Primary

Measure	Time frame
Quality of the contrast-enhanced images. Images will be marked 'high-quality / sufficient quality / insufficient quality'. The high- and sufficient quality images will be further analysed.	—

Secondary

Measure	Time frame
- Enhancement pattern and microvascular architecture of uteri (subjective description) - Full quantification of blood flow parameters from time-intensity curves, such as peak enhancement (maximal level of enhancement, associated with relative blood volume), rise time (time from baseline to peak enhancement, related to blood flow velocity), and wash-in rate (peak enhancement/rise time) using VueBox software (Bracco) and customized software by prof. M. Mischi (TU Eindhoven). - Power calculation for further research	—

Measure

Time frame

- Enhancement pattern and microvascular architecture of uteri (subjective description) - Full quantification of blood flow parameters from time-intensity curves, such as peak enhancement (maximal level of enhancement, associated with relative blood volume), rise time (time from baseline to peak enhancement, related to blood flow velocity), and wash-in rate (peak enhancement/rise time) using VueBox software (Bracco) and customized software by prof. M. Mischi (TU Eindhoven). - Power calculation for further research

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Countries

Netherlands

Outcome results