The impact of aerobic exercise pre-conditioning to maximize the skeletal muscle adaptive response to resistance type exercise training in healthy older adults

The impact of aerobic exercise pre-conditioning to maximize the skeletal muscle adaptive response to resistance type exercise training in healthy older adults - AERCO study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON52892

Enrollment

Registered

2019-02-06

Start date

2019-05-06

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenie age-related loss of muscle mass sarcopenia

Interventions

Participants will be randomly allocated to perform 8 weeks of aerobic pre-conditioning (AER) or no exercise control (CON) group. During aerobic pre-conditioning, participants will perform exercise f

Eligibility

Age

65 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Aged between 65-85 - Healthy - 18 * BMI * 30 kg/m2

Exclusion criteria

Exclusion criteria: - Smoking - Diabetes - Cardiovascular disease - Participation in any structured training program

Design outcomes

Primary

Measure	Time frame
Type II muscle fiber size (muscle biopsy)	—

Secondary

Measure	Time frame
Whole body- and regional body composition (DEXA and MRI scan), muscle strength and physical performance (1RM, SPPB, TUG, handgrip strength), muscle fiber characteristics (muscle biopsy), microvascular perfusion (CEUS) and oral glucose tolerance (OGTT) will be secondary parameters.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)