Angststoornissen en symptomen (posttraumatische stressstoornis) Eating disorder Posttraumatic stress disorder PTSD
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Study 1: - Female outpatients with anorexia nervosa, or otherwise specified feeding or eating disorder with anorexia nervosa symptoms (atypical AN) and posttraumatic stress disorder diagnosis according to DSM-5 - Age 18-65 - Body Mass Index >=15 - Informed consent - Enrollment in outpatient eating disorder treatment Study 2: - Female outpatients with bulimia nervosa, binge eating disorder, otherwise specified feeding or eating disorder with bulimia nervosa or binge eating disorder symptoms and posttraumatic stress disorder diagnosis according to DSM-5 - Age 18-65 - Body Mass Index >=15 - Informed consent - Enrollment in outpatient ED treatment
Exclusion criteria
Exclusion criteria: Study 1: - Current PTSD treatment - Other concurrent psychological treatment during the duration of the study than the studied intervention of exposure therapy and TAU for ED. - DSM-5 diagnosis of BN, BED, OSFED with BN or BED symptoms, Avoidant Restrictive Food Intake Disorder, night eating syndrome or purging disorder - Psychotic disorder - Medical instability (hospital admission required) or pregnancy - Changes in psychotropic medication in the two months prior to inclusion - High risk of suicidality in the last two months (High suicidality score on MINI-plus and a suicide attempt in the past 6 months) - Severe non-suicidal self-injury (NSSI) in the last two months (hospital referral required) - Insufficient proficiency in the Dutch language - Alcohol or drug dependency in last two months - Cognitive impairment (estimated IQ
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameter is decrease of weekly measured PTSD symptom severity after the onset of exposure therapy compared to baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary parameters are to investigate the feasibility of exposure therapy for PTSD in ED population, to measure the initial effect of exposure therapy on secondary clinical outcomes and to measure whether the intervention effects are maintained over time. | — |
Countries
Netherlands