Remote assessment of Disease and Relapse - Alzheimer's Disease

Remote assessment of Disease and Relapse - Alzheimer's Disease - RADAR-AD

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52829

Enrollment

Registered

2020-07-14

Start date

2020-08-21

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer's Disease Dementia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All subjects: - Over 50 years of age - Study partner available - In otherwise good health condition or with diagnosis mild chronic disorder or any other affections that are controlled by therapy and/or do not impair function on a secondary basis to that of AD-related symptomatology. - Subject and study partner own a smartphone Additional for subjects with Alzheimer's Disease: - Diagnosis of Alzheimer's Disease based on the presence of amyloid load AD biomarkers Additional for healthy controls: - No cognitive deficits at the screening visit Additional for probable bvFTD (n =15) - Diagnosis of probable bvFTD based on diagnostic criteria of Rascovsky et al., 2011 - FTDL-CDR (0-1)

Exclusion criteria

Exclusion criteria: - Presence of an additional neurological or psychiatric disease that may affect ADL or social interactions. - Any other kind of disorders that relevantly affect mobility and/or ADL or social interac-tions

Design outcomes

Primary

Measure	Time frame
Difference between healthy volunteers, preclinical AD, MCI due to AD, and mild-to-moderate AD and FTD in outcome measures of ADL using selected RMTs.	—

Secondary

Measure	Time frame
Difference between healthy volunteers, preclinical AD, MCI due to AD, and mild-to-moderate AD and FTD in the following assessments performed in the clinic or in real-life of the following: 1) difficulties at work; 2) spatial navigation & memory; 3) planning skills; 4) managing finances; 5) self-care; 6) self-management; 7) acquiring new skills; 8) sleep quality and cardiac rhythms; 9) use of technology/devices; 10) dysnomia, word finding difficulties; 11) gait; 12) difficulties driving; 13) interpersonal interaction; 14) motivation, signs of apathy or withdrawal.	—

Measure

Time frame

Difference between healthy volunteers, preclinical AD, MCI due to AD, and mild-to-moderate AD and FTD in the following assessments performed in the clinic or in real-life of the following: 1) difficulties at work; 2) spatial navigation & memory; 3) planning skills; 4) managing finances; 5) self-care; 6) self-management; 7) acquiring new skills; 8) sleep quality and cardiac rhythms; 9) use of technology/devices; 10) dysnomia, word finding difficulties; 11) gait; 12) difficulties driving; 13) interpersonal interaction; 14) motivation, signs of apathy or withdrawal.

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Countries

Netherlands

Outcome results