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Neural representations of food stimuli in Anorexia Nervosa

Neural representations of food stimuli in Anorexia Nervosa - NeuralRepAN

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON52810
Enrollment
45
Registered
2019-10-30
Start date
2020-08-17
Completion date
Unknown
Last updated
2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia nervosa eating disorder

Interventions

None listed

Sponsors

Universiteit Maastricht
Lead Sponsor

Eligibility

Age
16 Years to 64 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: Anorexia Nervosa: 1. Female 2. Have a current diagnosis of Anorexia Nervosa (restrictive subtype) 3. Be a patient at MUMC (or other participating medical centres) 4. Have a BMI between 13 and 18 5. Be able to give informed consent 6. Must be >= 16 years of age 5.7. Able to speak and read Dutch 6.8. Not allergic or intolerant to the liquid stimulidairy drinks Healthy Control: 1. Female 2. Not have a current or previous (within the past five years) diagnosis of an eating disorder, anxiety, depression and or OCD. 3. Have a healthy BMI (18.5 - 25). 4. Be able to give informed consent. 4.5. Must be >= 16 years of age 5.6. Able to speak and read Dutch. 6.7. Not allergic or intolerant to the liquid stimuli

Exclusion criteria

Exclusion criteria: For all participants:. 1. Allergies or Intolerances to ingredients contained in the liquid stimuli 2. Left-handedness 3. Existing medically diagnosed neurological disorders 4. Standard fMRI exclusion criteria (e.g., metallic medical devices or implants, pregnancy, piercings that cannot be removed). See E2 appendix C of the submitted file.

Design outcomes

Primary

MeasureTime frame
Study 1: The effect of these manipulated attentional focus on brain regions related to inhibitory control and reward processing. Study 2: The effect of informed and uninformed food caloric content on neural expectancy response and initial neural taste response.

Secondary

MeasureTime frame
Study 2: The effect of palatability vs tension on neural activity while tasting food.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)