Bleeding Diverticular disease
Conditions
Interventions
Group A: polyethylene glycol (OTC) twice daily, for the period of 12 weeks.
Group B: psyllium fiber (OTC) twice daily, for the period of 12 weeks.
Sponsors
Elisabeth-Tweesteden ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients between the ages of 18 or older. Patients who are hospitalized for bleeding diverticular disease in het ETZ. Patients with diverticular disease based on colonoscopy, sigmoïdscopy or CT-scan
Exclusion criteria
Exclusion criteria: Other bleeding diseases of the colon requiring medicinal treatment such as IBD or infection Surgical treatment following initial episode of bleeding diverticular disease. Patients using polyethylene glycol or psyllium fiber regularly, more than twice daily. Patients who are pregnant, lactating or planning pregnancy while enrolled in the study. Patients who are unsuitable for inclusion in the study in the opinion of the investigator for any reason that may compromise the subject*s safety or confound data interpretation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint of this study is the difference in incidence of rebleeding measured by preformatted questionnaire and clinical data between the polyethylene glycol vs psyllium fiber group. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary endpoints of the study are the differences in quality of live indicated by the EuroQol questionnaire, stool frequency and - consistency measured by the Bristol Stool Scale and diverticular disease activity measured by standard clinical and laboratory assessments. | — |
Countries
Netherlands
Outcome results
None listed