Depression Major Depressive Disorder (MDD)
Conditions
Interventions
None listed
Sponsors
Universiteit Leiden
Eligibility
Age
12 Years to 64 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria:, Adolescents in depressive group: • Aged between 11-17 years. • Living with at least one primary caregiver • At least one primary caregiver is willing to participate in the study • Current depressive episode (having symptoms at least 2 months prior to the diagnostic interview) • Major depressive disorder as primary diagnosis, Adolescents in control group: • Aged between 11-17 years. • Living with at least one primary caregiver • At least one primary caregiver is willing to participate in the study
Exclusion criteria
Exclusion criteria: Adolescents with major depressive disorder: • Primary psychiatric disorder (Axis I), other than MDD. • Comorbid eating disorders/mental retardation/psychoses/addictions (SUD) • Use of antidepressants (i.e. SSRIs or TCAs), unless in a constant dosage. • No good command of the Dutch language, Adolescents in the control group: • Current psychiatric disorder • History of psychiatric disorder in the past two years • Lifetime depressive episode • History of psychotherapy or other psychological treatment • No good command of the Dutch language • Use of medication for mental disorders or sleep medication, Additional fMRI exclusion criteria: • Metal implants, clips, stents, or pacemakers • Braces • Current pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| We will study the quality of the parent-child interactions, primarily based on the influence of parental criticism and empathy and the adolescent's mood. We will also investigate the predictive value of the interactions on the course of the complaints of the adolescents, controlled for possible treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| N.A. | — |
Countries
Netherlands
Outcome results
None listed