endometriose Endometriosis
Conditions
Interventions
None listed
Sponsors
Haaglanden Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Cases: - Aged between 18-40 years. - (1) diagnosed with endometriosis by laparoscopy OR (2) diagnosed with deep invasive endometriosis (DIE) by MRI after positive gynecological examination and subsequent ultrasound. Controls: - Aged between 18-40 years. - Conformed absence of endometriosis by laparoscopy (e.g. sterilization, extra-uterine pregnancy, diagnostic in case of infertility) or laparotomy (e.g. cesarean section).
Exclusion criteria
Exclusion criteria: - Underage women (40 years - Pregnancy or currently breastfeeding - Diagnosed adenomyosis without endometriosis - Alcohol consumption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome consist of exhaled breath profiles obtained by sampling exhaled breath using eNose technology. These profiles form a characteristic fingerprint of the Volatile Organic Compounds (VOC*s) present in exhaled breath. The profiles of both endometriosis patients and healthy controls will be analysed and compared to determine the sensitivity and specificity of the eNose technology in diagnosing endometriosis. | — |
Secondary
| Measure | Time frame |
|---|---|
| The sensitivity and specificity of the eNose technology in differentiating between early and advanced stages of endometriosis. | — |
Countries
Netherlands
Outcome results
None listed