cognitive impairment in mood disorders impairment of memory and attention in depression and mania
Conditions
Interventions
The intervention consists of a functional remediation program, based on
strategies for the treatment of patients with acquired brain injury (Sohlberg
en Mateer, 2001, Wilson, 2003, Haskins, 2012). T
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: o Age: 18-60 o Bipolar I Disorder or recurrent Major Depression according to DSM 5 as diagnosed by a psychiatrist and verified by MINI-Plus o Subjective cognitive complaints o At least moderate levels of functional impairments, Functioning Assessment Short Test (FAST) interview > 18 o NLV (Dutch National Adult Reading Test) IQ > 85 o Informed consent signed by patient before participation o Availability of a computer with internet and sufficient computer skills o Being able to read and write in Dutch o Mentally competent as documented in the formal treatment plan.
Exclusion criteria
Exclusion criteria: oCurrent mania or severe depression (defined by scores > 5 on the Altman Self-Rating Mania Rating Scale and >15 on the Quick Inventory of Depressive Symptoms) o Substance or alcohol abuse within the last 3 months (de*ned as more than 2 units/day for men, and more than 1 unit/day for women). o A history of neurological disease or traumatic brain injury o Electroconvulsive treatment (ECT) within the last 12 months o Currently participating in a group-treatment, or planning to participate within 3 months after the intervention. oPrior participation in the study *A pilot study of a combined group and individual functional remediation program for patients with bipolar I disorder*.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter will be the feasibility of the program as defined by the evaluations of the participants on closed and open ended questions and the non-compliance and drop-out rate and reasons for dropout and non-compliance. The two variants, fully offered online and blended, will be compared to each other on these variabels. In addition the experiences with the online application " Niet rennen maar plannen" will be evaluated through ratings on closed questions. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary study parameters will be the indication of change in subjective cognitive complaints, functional improvement and change expressed in QALYs. | — |
Countries
Netherlands
Outcome results
None listed