Effect of ageing on interpretation of disease activity measures and on cognition, physical activity and performance in patients with rheumatic disorders.

Effect of ageing on interpretation of disease activity measures and on cognition, physical activity and performance in patients with rheumatic disorders. - STudying Ageing in Rheumatic diseases (STAR)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52497

Enrollment

840

Registered

2021-06-01

Start date

2022-12-13

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

musculoskeletal disorders Rheumatic diseases

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Inclusion criteria, RA population - Age between 55 - 85 years at baseline. - Diagnosis of RA by treating rheumatologist. - Patients > 80 years who are physically unable to complete the whole study procedure (i.e. geriatric patients who are considered frail by the rheumatologist and/or patient itself), are allowed to undergo only part of the study measurements. The rheumatologist who invites a patient > 80 years explains this option to the patient; the patient is then allowed to choose which measurement protocol suits him/her best. Inclusion criteria, control population - Age between 55 - 85 years at baseline. - No diagnosis of RA, or other inflammatory RMD (osteoarthritis allowed). - Controls > 80 years who are physically unable to complete the whole study procedure (i.e. geriatric controls who are considered frail), are allowed to undergo only part of the study measurements. The research assistant who contacts the control after a control indicated his/her interest in the study, explains this option to the control; the control is then allowed to choose which measurement protocol suits him/her best.

Exclusion criteria

Exclusion criteria: Exclusiecriteria: - Have severe comorbidity and the treating rheumatologist or research team decides they should not be included in the study because of health reasons. - Do not understand the Dutch language and/or are not able to understand the study information.

Design outcomes

Primary

Measure	Time frame
Primary objective: to investigate how measures of disease activity and measures for cognition, physical activity and performance behave in ageing population controls and RA patients. If an differential effect of age on outcome over time is apparent, the presence of an inclination point will be assessed.	—

Secondary

Measure	Time frame
Secondary objective: in case of differences between ageing RA patients and population controls, we will also investigate what additional factors might explain these differences.	—

Countries

Netherlands

Outcome results