Alle patienten met een primaire diagnose van kanker Cancer patients at the end of life with untreatable symptoms Terminal cancer patients with refractory symptoms
Conditions
Interventions
None listed
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Age 18 years or above; * Primary diagnosis at admission is advanced cancer; * Life expectancy of the patient is limited (clinical prognosis estimation 1-2 months); * Intractable distress caused by one or more refractory symptoms during the hospitalization can be expected or is present, according the health care team; * Able to give informed consent, or there is a possibility of proxy informed consent.
Exclusion criteria
Exclusion criteria: * When a potential participant is unable to give informed consent and there is no possibility of proxy informed consent, he/she is not eligible for participation in this study. * When a potential participant and/or the relative is unable to speak and read in the native language of the participating country, he/she is not eligible for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in discomfort levels of patients receiving palliative sedation, measured by the health care professionals using the DS-DAT, a Discomfort Score for patients with Dementia Alzheimer Type. Measured before and twice a day during the whole procedure of palliative sedation until death. This measure has been succesfully applied in sedated patients in previous studies, for example from Radboudumc. | — |
Secondary
| Measure | Time frame |
|---|---|
| Depth of sedation and levels of agitation are measured with the Richmond Agitation Sedation Scale, modified version for palliative care (RASS-PALL). | — |
Countries
Netherlands
Outcome results
None listed