Leukapheresis of healthy volunteer donors for T cell study and TolDC production process validations

Leukapheresis of healthy volunteer donors for T cell study and TolDC production process validations - Cell therapy study testruns healthy volunteer donors

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52474

Enrollment

Registered

2019-04-17

Start date

2023-01-09

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hematological and immunological diseases Diseases of the blood, the immune system, and the lymph nodes

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: -Age > 17 years -Able to comprehend and give signed informed consent

Exclusion criteria

Exclusion criteria: -Any concurrent systemic comorbidity -Symptoms of infectious disease in the 3 weeks prior to donation -Vaccination of any kind in the 3 weeks prior to donation -Requirement for additional infectious disease screening -Insufficient vascular access for the purpose of the apheresis procedure -Pregnancy -Any condition that in the opinion of the IHB medical team might interfere with the safe completion of an apheresis procedure

Design outcomes

Primary

Measure	Time frame
Successful collection of sufficient numbers of MNC for T cell or monocyte isolation for the purpose of testruns and validation procedures for T cell or tolerogenic dendritic cell studies.	—

Secondary

Measure	Time frame
None	—

Countries

Netherlands

Contacts

Public ContactC.S. Ootjers

Leids Universitair Medisch Centrum

stafsecretariaathematologie@lumc.nl+31 71 – 52 62261

Outcome results