The uptake of radioactive iodine before and after a low iodine diet in patients with differentiated thyroid carcinoma

The uptake of radioactive iodine before and after a low iodine diet in patients with differentiated thyroid carcinoma - Iodine uptake after LID

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52405

Enrollment

Registered

2019-07-30

Start date

2023-02-17

Completion date

Unknown

Last updated

2026-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

differentiated thyroid carcinoma (DTC) thyroid cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients, men and women above the age of 18 years, have to be diagnosed with DTC and have to follow a LID prior to the 131I therapy according to the Dutch DTC guideline - Patients have to be fit to adhere to the study protocol - Patients have to be able to read and understand the Dutch language

Exclusion criteria

Exclusion criteria: - Age

Design outcomes

Primary

Measure	Time frame
Main study parameter/endpoint The primary endpoint is the clinical relevant difference of a twofold uptake increase, in the thyroid remnant after thyroidectomy in DTC patients, of 10 MBq 123I tracer dose before and after a LID of 7 days.	—

Secondary

Measure	Time frame
Secondary study parameters/endpoints - Compliance to the LID will be evaluated by measuring the UIE before and after the LID. - Clinical cut-off values of SIE for sufficient, insufficient and, deficient, iodine status will be determined based on UIE.	—

Countries

Netherlands

Outcome results