testing if the fallopian tubes are open Tubal patency testing
Conditions
Interventions
We will compare tubal flushing with oil-based contrast (intervention) versus
tubal flushing with water-based contrast (control).
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Women: 1: with ovulation disorders (defined as less than 8 menstrual cycles per year) or; 2: at high risk for tubal pathology (defined as a positive chlamydia infection, a pelvic inflammatory disease, known endometriosis, abdominal surgery (including tubectomy for ectopic pregnancy and appendectomy) and/or peritonitis in the medical history) or; 3: above 38 years of age
Exclusion criteria
Exclusion criteria: - Iodine allergy - Male subfertility defined as a post-wash total motile sperm count
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome is conception leading to live birth within 6 months after randomization. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Biochemical pregnancy - Clinical pregnancy - Ongoing pregnancy - Miscarriage - Ectopic pregnancy - Multiple pregnancy - Complications following HSG (infection, intravastion) - Pregnancy outcomes (f.e. birth weight) - Pregnancy complications - Stillbirth - Thyroid function of the woman (before and 1 month after HSG) - Neonatal outcomes - Additional fertility treatments (Intra-uterine insemination, IVF, IVF/ICSI) - Costs within 6 months after randomization - Thyroid function of neonate (determined by heelprick) | — |
Countries
Netherlands
Outcome results
None listed