Towards lifelong healthy LUNGS: a multidisciplinary follow-up framework for preterm infants.

Towards lifelong healthy LUNGS: a multidisciplinary follow-up framework for preterm infants. - LONG LOVE

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON52324

Enrollment

330

Registered

2022-01-27

Start date

2022-07-18

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lower Respiratory Tract Infections

Interventions

Follow-up regimen after premature birth using the LONG LOVE framework: Identification of modifiable influencing factors Five study visits are scheduled to monitor health status on 1-1.5*, 3, 6, 12 a

DCMR Milieudienst Rijnmond). This network consists of a large number of air quality measurement sites, measuring harmful substances: nitric oxides (NOx, NO2), particulate matter (PM2.5, PM10) and o

Eligibility

Age

No minimum to 1 Years

Inclusion criteria

Inclusion criteria: Moderate-late preterm infants (GA 30+0 - 35+6 weeks) without any other significant underlying morbidity

Exclusion criteria

Exclusion criteria: Underlying other severe respiratory diseases such as bronchopulmonary dysplasia (BPD); diaphragmatic hernia, other serious cogenital pulmonary disorders; hemodynamic significant cardiac disease; immunodeficiency; severe failure to thirve; birth asphyxia with poor neurological outcome; syndromic or serious congenital disorders

Design outcomes

Primary

Measure	Time frame
Total number of physician diagnosed lower RTI and wheezing episodes in the first 18 months of life.	—

Secondary

Measure	Time frame
time to first lower RTI or wheezing episode total number of RTI total number of wheezing episodes distribution of viruses (in case of hospital admission) medication use (bronchodilators, corticosteroids, antibiotics) lung function as measured by expiratory variability index and relation with LRTI/wheezing comparison of expiratory variability index in moderate/late prematurity compared to term cohort (reference cohort from other center) correlation between expiratory variability index and other pulmonary function analyses association between expiratory variability index and number of RTI/wheezing outdoor air quality indoor air quality association between air quality and number of RTI quality of life classification of high-risk patients costs- and cost-effectiveness	—

Measure

Time frame

time to first lower RTI or wheezing episode total number of RTI total number of wheezing episodes distribution of viruses (in case of hospital admission) medication use (bronchodilators, corticosteroids, antibiotics) lung function as measured by expiratory variability index and relation with LRTI/wheezing comparison of expiratory variability index in moderate/late prematurity compared to term cohort (reference cohort from other center) correlation between expiratory variability index and other pulmonary function analyses association between expiratory variability index and number of RTI/wheezing outdoor air quality indoor air quality association between air quality and number of RTI quality of life classification of high-risk patients costs- and cost-effectiveness

—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)