airway clearance - mucociliary clearance respiratory secretion accumulation
Conditions
Interventions
Bedside nurses, trained in using the MI-E device, will apply MI-E sessions at
two moments per calendar day (morning and afternoon) for a maximum of 7 days
while a patient is invasively ventilated. A
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • admission to one of the participating ICUs; and • intubated with an endotracheal tube; and • expected to need invasive ventilation for more than 48 hours from consideration for inclusion.
Exclusion criteria
Exclusion criteria: age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the proportion of delivered MI-E sessions (2 times a MI-E session of 3 cycles per calendar day) per patient according to study protocol (feasibility). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are the total number of serious adverse events (incidence of pneumothorax and serious hemodynamic of pulmonary instability) in relation to MI-E (safety) and preliminary exploratory data on clinical outcomes including duration of invasive ventilation, length of stay in ICU and mortality (efficacy). | — |
Countries
Netherlands
Outcome results
None listed