Feasibility of ultrasound particle image velocimetry to quantify flow in the abdominal aorta before and after endovascular aneurysm repair

Feasibility of ultrasound particle image velocimetry to quantify flow in the abdominal aorta before and after endovascular aneurysm repair - EchoPIV in AAA trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52210

Enrollment

Registered

2021-07-21

Start date

2022-07-06

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Abdominal aortic aneurysm enlargement of the large blood vessel

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Male or female > 18 years of age - BMI * 30 kg/m2 - Infrarenal AAA - Scheduled for elective EVAR - Informed consent form understood and signed, and agrees to all visits

Exclusion criteria

Exclusion criteria: - Hypersensitivity to the active substance(s) or any of the excipients in Sonovue - Right-to-left cardiac shunt - Severe pulmonary hypertension (pulmonary artery pressure > 90mmHg) - Uncontrolled systemic hypertension - Severe pulmonary disease (e.g. COPD GOLD 3 or 4, adult respiratory distress syndrome) - Clinically unstable cardiac disease (recent,

Design outcomes

Primary

Measure	Time frame
Vector velocity data derived from the echoPIV analysis will be used to calculate and visualize the spatiotemporal blood flow velocity profiles.	—

Secondary

Measure	Time frame
- Vector velocity data derived from the PC MRI scan will be used to calculate and visualize the spatiotemporal blood flow velocity profiles and to validate the echoPIV results. - Pre- and postoperative spatiotemporal velocity profiles obtained with echoPIV will be compared to evaluate the influence of the placement of a stent graft on local hemodynamics. - From both datasets blood flow derived parameters, such as vector complexity and vorticity, will be calculated. Moreover, specific blood flow patterns like recirculations or blood stasis will be evaluated thoroughly.	—

Measure

Time frame

- Vector velocity data derived from the PC MRI scan will be used to calculate and visualize the spatiotemporal blood flow velocity profiles and to validate the echoPIV results. - Pre- and postoperative spatiotemporal velocity profiles obtained with echoPIV will be compared to evaluate the influence of the placement of a stent graft on local hemodynamics. - From both datasets blood flow derived parameters, such as vector complexity and vorticity, will be calculated. Moreover, specific blood flow patterns like recirculations or blood stasis will be evaluated thoroughly.

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Countries

Netherlands

Outcome results