stomach and esophagus cancer upperGi cancer
Conditions
Interventions
None listed
Sponsors
Antoni van Leeuwenhoek Ziekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • histologically proven cT2-4aN0-2 adenocarcinoma carcinoma of the oesophagus, gastroesophageal junction or stomach. • histologically proven metastases from esophageal or gastric cancer or if histologic biopsy is not possible, radiological images are highly suspicious for metastases • Maximum of 3 metastases in one organ OR M1 lymph node metastasis restricted to one region (brain metastases are allowed) • Resectable primary tumor. • Metastases eligible for adequate local treatment. • good performance status (WHO performance status 0-2) (appendix I). • ASA 1-2 (appendix II). • written informed consent. • age >= 18 • fit to receive palliative systemic treatment
Exclusion criteria
Exclusion criteria: • pregnancy, lactating female • peritoneal metastases or positive cytology from abdominal washings. • patients participating in other trials that would interfere with the implementation of this protocol. • Patients with N3M1 disease • Unable or unwilling to undergo systemic palliative treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| progression free survival | — |
Secondary
| Measure | Time frame |
|---|---|
| -safety -quality of life - overall survival - whether ctDNA can help us better select the right patients in the future who will benefit from this treatment | — |
Countries
Netherlands
Outcome results
None listed