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How does the brain learn about positive and negative things?

How does the brain learn about positive and negative things? - Learning and Decision-making (LDM)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON52086
Enrollment
150
Registered
2020-12-17
Start date
2021-05-11
Completion date
Unknown
Last updated
2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

psychologische functies instrumental learning

Interventions

None listed

Sponsors

Dept. Psychiatry
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Age 18-35 BMI 17.5-30

Exclusion criteria

Exclusion criteria: Psychiatric (including substance abuse/dependence) or neurological disorder Current treatment with a psychoactive medication Contraindications for haloperidol or propranolol

Design outcomes

Primary

MeasureTime frame
The primary outcome is the task performance on two cost-benefit evaluation tasks.

Secondary

MeasureTime frame
Additional parameters include catecholamine (alpha-amylase) and neuroinflammatory (TNF-a, IL-6, IL-1*), markers measured non-invasively in saliva.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)