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The effect of indoor carbon dioxide on cognition

The effect of indoor carbon dioxide on cognition - CO2CE

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON52064
Enrollment
20
Registered
2021-07-28
Start date
2021-10-29
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N/a, the study is about the cognitive performance of healthy participants air quality

Interventions

The indoor CO2 concentration in the respiratory chambers will vary between the two tests days. It will be either 800 ppm (0.08%) high, or 3000 ppm (0.3%) high.

Sponsors

Nutrition and Movement Sciences (VBW)
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - Adults: 25 to 50 years old - White-collar workers: Participants that conduct cognitive task and low physical effort on a daily basis - BMI between 18.5 and 25 - Generally healthy, no medication, except for contraceptives for woman - Non-smokers or person who quit smoking more than five years ago

Exclusion criteria

Exclusion criteria: - Persons who are unemployed - Persons with a disorder or disease (Parkinson, Attention Deficit Hyperactivity Disorder (ADHD), Alzheimer, diabetes, cardiovascular disorder, respiratory impairments (for example asthma), hypertension, obesity, or any other condition that can impair the lung function) - Athletes: no individuals who do endurance sports on a professional basis or more than 5 times a week for more than 2 hour - Any medication or medical condition that might interfere with the physiological outcome parameters or in some regards impair cognition - Individuals with a high level of caffeine consumption (determined by the validated Caffeine Consumption Questionnaire [Irons et al]) - Shift workers - Color blindness - Pregnancy

Design outcomes

Primary

MeasureTime frame
The main study parameters is the test scores of the CANTAB cognition tests.

Secondary

MeasureTime frame
The secondary parameters are the choices in the lotteries determining risk and time preferences, the answers from questionnaires about risk and time preferences, the changes in metabolic energy expenditure, as well as the following physiological parameters: heart rate variability, CO2 blood concentration, O2 saturation level, physical activity level, blood pressure, skin temperature, and breathing rate. Subjects will also receive a heuristics battery survey at the end of the test day, which measures the sensitivity to bias behavior. This includes measuring if automatic processes are tended to make more often than deliberative decisions in order to solve a problem.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)