Recognizing patients with (a higher risk of) endometrial cancer; the rol of fat distribution and inflammation in the origin of endometrial cancer, a study that focuses on prevention and prediction

Recognizing patients with (a higher risk of) endometrial cancer; the rol of fat distribution and inflammation in the origin of endometrial cancer, a study that focuses on prevention and prediction - ENDOCRINE (ENDOmetrial Cancer pReventIon aNd prEdiction)

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52042

Enrollment

160

Registered

2021-07-20

Start date

2021-11-08

Completion date

Unknown

Last updated

2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cancer of the womb Uterine cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Cases: Subjects with endometrial cancer/hyperplasia with atypia, who are planned for hysterectomy with bilateral salpingo-oophorectomy. Controls: Subjects who are planned for bilateral salpingo-oophorectomy without malignancy and are older than 40

Exclusion criteria

Exclusion criteria: Malignancy 5 years prior to inclusion (basal cell carcinoma excluded) Use of systemic hormonale therapy the past 12 months inadequate knowledge of the Dutch language Contra-indication for ct-scan

Design outcomes

Primary

Measure	Time frame
Hormone levels and inflammation markers after BSO depending on BMI	—

Secondary

Measure	Time frame
Effect of fat distribution on hormone levels and inflammation markers Effect of BSO on subjects complaints (depending on BMI)	—

Countries

Netherlands

Outcome results