Multiple sclerosis lesion characterization on ultra-high-field MRI: Comparative pilot study of 9.4 vs 7 vs 3 tesla

Multiple sclerosis lesion characterization on ultra-high-field MRI: Comparative pilot study of 9.4 vs 7 vs 3 tesla - ULTIMS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52035

Enrollment

Registered

2022-02-21

Start date

2023-09-12

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MS multiple sclerosis

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Relapsing remitting MS patients (according to the 2017 McDonald criteria) between age 18-65 years, who had a new brain MRI lesion in the past 15 months. Choosing an upper limit of 65 years, limits the age-related vascular white matter lesion burden on the brain scans.

Exclusion criteria

Exclusion criteria: Patients who are unable to undergo MRI investigations due to (i) non-compatible implanted material/devices or (ii) due to not being able to lie flat long enough because of another medical condition, will be excluded.

Design outcomes

Primary

Measure	Time frame
Difference in white matter lesion volume/count, cortical lesion volume/count, percentage of lesions with central veins, tolerability of the investigation, between the field strengths, quantitative image quality parameters (signal- and contrast-to- noise ratios).	—

Secondary

Measure	Time frame
.	—

Countries

Netherlands

Outcome results