Whole body muscle MRI in Myasthenia gravis

Whole body muscle MRI in Myasthenia gravis - Whole body muscle MRI in Myasthenia gravis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52030

Enrollment

Registered

2021-03-19

Start date

2021-09-30

Completion date

Unknown

Last updated

2026-03-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Myasthenia Myasthenia gravis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Definitive diagnosis of MG defined as the presence of serum autoantibodies (anti-acetylcholine receptor [AChR], anti-muscle specific tyrosine kinase [MuSK])

Exclusion criteria

Exclusion criteria: - Subjects who are not legally capable - Subjects under the age of 18 - No (other) diagnosis of neuromuscular disease or chronic lesions to the musculoskeletal system - Contraindications to MRI scanning - In healthy controls: the use of anabolic steroids

Design outcomes

Primary

Measure	Time frame
The main study parameters are fat fraction, the muscle volume and the amount of positive T2-STIR lesions.	—

Secondary

Measure	Time frame
The secondary study parameters are the scan protocol toleration by patients, the visibility of all muscles and the robustness of the quantitative data.	—

Countries

Netherlands

Outcome results