Endoscope CRC cohort: Development and evaluation of diagnostic and prognostic biomarker profiles for colorectal cancer and premalignant lesions

Endoscope CRC cohort: Development and evaluation of diagnostic and prognostic biomarker profiles for colorectal cancer and premalignant lesions - Endoscope CRC cohort

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON52029

Enrollment

2000

Registered

2021-05-03

Start date

2021-11-11

Completion date

Unknown

Last updated

2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal adenoma colorectal cancer

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adult subjects participating in the Dutch national bowel cancer screening program with positive iFOBT, with an indication, physical fitness and consent to undergo a colonoscopy.

Exclusion criteria

Exclusion criteria: Previous history of colorectal cancer. History of any malignant disease

Design outcomes

Primary

Measure	Time frame
Main parameters are: non-invasive biomarkers in exhaled air, blood plasma/serum, and faeces.	—

Secondary

Measure	Time frame
Secondary parameters are: patient characteristics, characteristics of the identified pre-malignant and malignant colonic lesions, quality of life, and gastrointestinal symptom scores pre-, during and post-treatment, recurrence rates of CRC, survival rates.	—

Countries

Netherlands

Outcome results