Protecting against Respiratory tract Infections through human Milk Analysis.

Protecting against Respiratory tract Infections through human Milk Analysis. - PRIMA

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51989

Enrollment

1000

Registered

2020-09-10

Start date

2021-05-25

Completion date

Unknown

Last updated

2025-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia Respiratory tract infection

Interventions

None listed

Eligibility

Age

No minimum to 64 Years

Inclusion criteria

Inclusion criteria: All healthy childen (and their parents) born at a minimal gestational age of 32 weeks.

Exclusion criteria

Exclusion criteria: Exclusion criteria concerning the child: - Congenital heart defect. - Congenital lung disorder or other severe organ dysfunction. - (extreme) prematurtity (B1 CEFR level).

Design outcomes

Primary

Measure	Time frame
The amount of medically attended respiratory tract infections during the first year of life.	—

Secondary

Measure	Time frame
1. The amount of medically attended respiratory tract infections for every quarter of a year during the first year of life. 2. The amount of prescribed antibiotic treatments for respiratory tract infections during the first year of life. 3. The total amount of respiratory tract infection periods during every quarter of a year for the first year of life. 4. Food allergies diagnosed by a physician during the first year of life. 5. Inhalation allergies diagnosed by a physician during the first year of life. 6. Eczema diagnosed by a physician during the first year of life. 7. Maternal diet. 8. Macro- and micronutrient composition of breast milk. 8. Microbiota composition in feces. 9. Antibody repertoire and viral genome in saliva. 10. Extracellular vesicle repertoire in breast milk.	—

Measure

Time frame

1. The amount of medically attended respiratory tract infections for every quarter of a year during the first year of life. 2. The amount of prescribed antibiotic treatments for respiratory tract infections during the first year of life. 3. The total amount of respiratory tract infection periods during every quarter of a year for the first year of life. 4. Food allergies diagnosed by a physician during the first year of life. 5. Inhalation allergies diagnosed by a physician during the first year of life. 6. Eczema diagnosed by a physician during the first year of life. 7. Maternal diet. 8. Macro- and micronutrient composition of breast milk. 8. Microbiota composition in feces. 9. Antibody repertoire and viral genome in saliva. 10. Extracellular vesicle repertoire in breast milk.

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Countries

Netherlands

Outcome results