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Urea monitoring in plasma, sweat and saliva of patients during hemodialysis

Urea monitoring in plasma, sweat and saliva of patients during hemodialysis - Urea-monitoring in Sweat and Saliva (Umis Studie)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON51983
Enrollment
40
Registered
2021-08-12
Start date
2021-10-05
Completion date
Unknown
Last updated
2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hemodialysis Kidney diseases

Interventions

None listed

Sponsors

Catharina-ziekenhuis
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: The patient is treated with hemodialysis

Exclusion criteria

Exclusion criteria: - Age below 18 years old - Hospitalization for any reason other than hemodialysis treatment - Patients with an implanted device, such as a defibrillator, neurostimulator, pacemaker, or ECG monitor. - Patients with a history of epilepsy or seizures. - Patients who are pregnant. - Patients that have a known sensitivity or allergy to any used ingredient. - Over damaged, denuded skin or other recent scar tissue. - Patients with Cardiac Conditions or with suspected heart problems.

Design outcomes

Primary

MeasureTime frame
Endpoints: - Correlation coefficients and bias between urea concentration in plasma, sweat and saliva at the start (C0) and at the end (Ct) of hemodialysis and as a ratio (Ct/C0). - (Difference between) Kt/V values determined with urea concentrations in plasma, sweat and saliva - (Statistical difference between) the coefficients of the estimated curves for urea concentrations in saliva versus plasma during hemodialysis Parameters: - Urea concentrations in plasma, sweat and saliva at the start (C0) and at the end (Ct) of the hemodialysis - To calculate the Kt/V: ratio of urea concentrations (Ct/C0), time of hemodialysis (T), intradialytic body weight loss (dBW) and the body weight at the end of dialysis (BW)(formula 1). - Salivary and plasma urea concentrations at four time points during hemodialysis.—

Secondary

MeasureTime frame
Endpoint: - Correlation coefficients and bias between creatinine concentration in plasma, sweat and saliva at the start (C0) and at the end (Ct) of hemodialysis and as a ratio (Ct/C0). - (Statistical difference between) the coefficients of the estimated curves for creatinine concentrations in saliva versus plasma during hemodialysis. Parameters: - Creatinine concentrations in plasma, sweat and saliva at the start (C0) and at the end (Ct) of the hemodialysis - Salivary and plasma creatinine concentration at four time-points for saliva and blood during hemodialysis.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)