Midlife hypertension and structural and functional brain MRI: catching the first signs of cerebral small vessel disease

Midlife hypertension and structural and functional brain MRI: catching the first signs of cerebral small vessel disease - HYPERINTENSE

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51980

Enrollment

130

Registered

2020-12-03

Start date

2021-07-06

Completion date

Unknown

Last updated

2024-09-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension increased blood pressure

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Population 1: Hypertension, age between 18-40 years Population 2: Hypertension, age between 18-55 years (See section J. for more information)

Exclusion criteria

Exclusion criteria: Pre-existing cerebrovascular disease Pregnancy Contraindications for 3 T MRI Carotid artery stenosis > 50%

Design outcomes

Primary

Measure	Time frame
Neuroimaging markers of SVD	—

Secondary

Measure	Time frame
Measures of cognitive and motor functioning (using standardised tests and questionnaires), circulating markers of inflammation	—

Countries

Netherlands

Outcome results