congenital heart defect Congenital heart disease
Conditions
Interventions
Endocardial mapping during sinus rhythm and programmed electrical stimulation
before and after endovascular closure of the cardiac defect.
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: >=18 years; Scheduled for elective endovascular closure of atrial septal defect or patent foramen ovale
Exclusion criteria
Exclusion criteria: Paced atrial rhythms Pacemaker/ internal cardiac defibrillator (ICD) Hemodynamic instability Presence of assist devices Use of inotropic agents Emergency endovascular cardiac procedures Left ventricle ejection fraction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Quantification of electrophysiological parameters obtained from endocardial mapping that determine the degree of electropathology: conduction block, conduction delay, conduction velocity, signal morphology (voltage, fractionation). These parameters will be correlated with electropathology, atrial ectopy, atrial volume, clinical characteristics and features of pre- and post-procedural atrial fibrillation. | — |
Secondary
| Measure | Time frame |
|---|---|
| N.a. | — |
Countries
Netherlands
Outcome results
None listed