affective disorders depression
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1) Age >=60 years, 2) Affective disorder according to DSM-5 criteria, i.e. a depressive, anxiety and/or somatic symptom disorder, 3) Informed consent.
Exclusion criteria
Exclusion criteria: 1) An established diagnosis of a neurodegenerative disorder, 2) Cognitive impairment defined as scoring less than 18 points on the Montreal Cognitive Assessment (MoCA) test, 3) (History of a) bipolar or psychotic disorder, 4) Severe substance-use disorder in need of specialised treatment, 5) Physically or mentally too handicapped to administer self-report questionnaires or perform cognitive testing, 6) Insufficient mastery of the Dutch language.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome parameter for the full clinical cohort study is remission at one-year follow-up of the identified affective disorders at inclusion, and for the limited study, recovery at one-year follow-up as assessed by self-report questionnaire. Parameters for the full study in addition include a battery of potential confounders, with specific attention for age-specific characteristics regarding cognitive functioning (including global cognitive functioning as well as executive functioning, processing speed and episodic memory), physical functioning (including multimorbidity, polypharmacy, and physical frailty), and social functioning (loneliness, social network size, role limitations). | — |
Secondary
| Measure | Time frame |
|---|---|
| - | — |
Countries
Netherlands
Outcome results
None listed