Bell's Palsy
Conditions
Interventions
None listed
Sponsors
Medisch Universitair Ziekenhuis Maastricht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: (1) absence of facial nerve transposition; (2) participants must be 18 years of age or older; (3) signed informed consent. For patients who suffer from oral-ocular synkinesis, two extra criteria will be maintained: patients must have severe facial synkinesis based on the Sunnybrook facial grading system at the time the MRI scan is performed, and synkinesis must occur only on one side of the face.
Exclusion criteria
Exclusion criteria: The following exclusion criteria will be maintained for both the patients with facial synkinesis as the control participants: previous neurosurgery and contraindications for MRI investigation, such as a pacemaker, implanted pumps or stimulators, iron materials (e.g., piercings), facial tattoos and permanent make up, or claustrophobia. For control participants, one extra criteria will be maintained: the participant must have no forms of facial paralysis prior to the MRI examination and at the time of the MRI procedure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the hemodynamic response after stimulation of specific parts of the face. Within the areas of interest (primary motor cortex, the ventral lateral premotor cortex, the supplementary motor cortex, the primary somatosensory cortex (S1), the secondary somatosensory cortex (S2), the facial nucleus (pons), and the trigeminal nucleus (pons)), the temporo-spatial brain activity patterns after the different motor and sensory tasks are assessed, and the representation of the face is mapped on the cortexes of interest. | — |
Countries
Netherlands
Outcome results
None listed