hereditary high cholesterol
Conditions
Interventions
One blood sample will be collected on Day 1 (55 ml).
Sponsors
Beren Therapeutics P.B.C.
Eligibility
Age
12 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Patients clinically diagnosed using regional diagnostic criteria (e.g., Simon Broome, Dutch Lipid Network, MEDPED, etc.) and/or genetically confirmed diagnosis of Familial Hypercholesterolemia (FH) 2. >=12 years of age 3. Triglycerides =190mg/dL within last 30 days for untreated adults o >=150mg/dL within last 30 days for untreated children OR o >=160mg/dL within last 30 days for stably treated patients (adults & children)
Exclusion criteria
Exclusion criteria: 1. Conditions or circumstances that, in the opinion of the Investigator, could interfere with or confound study results, or preclude informed consent. 2. Liver transplant recipients. 3. Patients who have undergone partial ileal bypass surgery. 4. Patients with evidence in medical history of chronic HBV infection, HCV infection, or HIV infection 5.Patients who are currently participating or have participated in a clinical trial in which investigational intervention was administered within 12 weeks or 5 half-lives, whichever is longer, of Screening in this clinical study.
Countries
Netherlands
Outcome results
None listed