Gait impairment in Parkinsons disease Gait impairment in Parkinsons disease
Conditions
Interventions
At baseline, the efficacy of both external and internal cueing strategies will
be determined. Responders will be instructed to apply the effective cueing
strategies in daily life as much as possible
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Men and women of age > 18 years with idiopathic Parkinson*s disease; - Presence of disabling gait impairment; - Written informed consent.
Exclusion criteria
Exclusion criteria: - Usage of compensation strategies for the past six months; - Presence of deep brain stimulation (DBS); - Presence of severe co-morbidity limiting ambulation (e.g. stroke, orthopaedic problems); - Inability to walk unaided (with the exception of a customary cane); - Inability to walk for >3 minutes consecutively; - Severe auditory impairments, hampering perception of auditory cues; - Severe cognitive impairments, hampering the ability to comply to the study protocol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main parameter is the degree of cortical activation during walking, as measured by ambulatory high-density EEG. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters involve spatiotemporal parameters, including gait speed and stride length. The use of the application by responders will be recorded (expressed in frequency and duration). Responders additionally report the efficacy of cueing in daily life, which is expressed as the self-reported number of times using the strategy and the perceived efficacy using a five-point Likert scale during follow-up. | — |
Countries
Belgium, Israel, Italy, Netherlands
Contacts
Public ContactE.C. Albers
Radboud Universitair Medisch Centrum
Outcome results
None listed