Chronic bowel disease Inflammatory bowel disease
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - An established diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) - Receiving biological induction or maintenance therapy according to standard treatment protocols - 18 years of age or older - Written and signed informed consent
Exclusion criteria
Exclusion criteria: - Patients with a visual, physical or mental impairment, rendering them unable to use a capillary sampling device. - Patients unable to read or understand the Dutch language - Patients with severe Raynaud*s syndrome or digital ischemia - Unwillingness to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Concentrations of CRP and pharmacodynamic and pharmacokinetic domains of biological therapy (i.e., concentration of biological trough levels, concentration of antidrug antibody levels) measured in capillary samples compared to venous samples (standard procedure) | — |
Secondary
| Measure | Time frame |
|---|---|
| -Percentage of patients unable to provide a capillary sample -Patience experience of capillary sampling through finger prick at home, invistigated through a survey | — |
Countries
Netherlands
Outcome results
None listed