Exploring Metabolic Maturation in the Extremely Preterm Brain at Term Equivalent Age: EMMA study.

Exploring Metabolic Maturation in the Extremely Preterm Brain at Term Equivalent Age: EMMA study. - EMMA study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51783

Enrollment

Registered

2022-05-17

Start date

2023-06-22

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

born to early (

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: - EPT infants (

Exclusion criteria

Exclusion criteria: - Suspicion of congenital anomalies or syndromes; - Corpus alienum inside or outside the body of the infant that cannot be temporarily removed (i.e. ferrometal, pacemakers, cochlear implants, ventriculoperitoneal shunt, ductusclips, rickham reservoir, aneurysm clips); - Instable clinical condition (e.g. respiratory support / intravenous or intra-arterial catheters); - Very irritable or feeding intolerance or weight below 2.7 kg; - No parental written informed consent;

Design outcomes

Primary

Measure	Time frame
7 Tesla markers (MRS; CEST; SWI; PC-MRI), neuropsychological developmental outcome (ASQ-4; GM; HINE; Bayley-III).	—

Secondary

Measure	Time frame
3 Tesla prematurity (Kidokoro et al., 2013).	—

Countries

Netherlands

Contacts

Public ContactEC Wiegers

Universitair Medisch Centrum Utrecht

e.c.wiegers@umcutrecht.nl0887553197

Outcome results