Predictive model for the sensitising capacity of novel nutritional proteins.

Predictive model for the sensitising capacity of novel nutritional proteins. - PREFER study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51765

Enrollment

Registered

2022-07-07

Start date

2022-07-11

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

allergy Food hypersensitivity

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Signed informed consent 18 years of age or older, mentally competent Patients suspected of a food allergy to peanut, or cow's milk, or hen's egg Complaints after consuming peanut, or cow's milk, or hen's egg Positive Skin Prick test with peanut, or cow's milk, or hen's egg

Exclusion criteria

Exclusion criteria: Patient eats peanut, or cow's milk, or hen's egg, without complaints Negative skin prick test with peanut, or cow's milk, or hen's egg Negative DBPCFC with peanut, or cow's milk, or hen's egg Antihistamines used in the last 72 hours before the skin prick test and/or DBPCFC Unable to stop beta-blockers Use of more than 10 mg prednisone (relative contraindication)

Design outcomes

Primary

Measure	Time frame
IL-13 (biomarker) production by human donor blood cells in the new in vitro assays.	—

Countries

Netherlands

Outcome results