coordination disorder movement disorder
Conditions
Interventions
Wearing of the GyBAR backpacl
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - Diagnosis of pure degenerative ataxia based on molecular diagnosis or clinical assessment by a neurologist specialized in movement disorders - Age between 18-70 years old - Difficulties with gait where the participant cannot perform tandem walking (heels to toes) over ten steps and staggering occurs while performing a half turn (though it is possible to complete the turn without support (Score of 2 or 3 on item 1 *Gait* of the Scale for the assessment and rating of ataxia (SARA)) - Difficulties while standing that arise when the participant is asked to stand with feet together, whereas standing in natural position is possible for over 10 seconds; (Score of 3 on item 2 *Stance* of the SARA scale) - Being able to wear a backpack of 6 kilograms for a duration of two hours
Exclusion criteria
Exclusion criteria: - Other neurological or orthopaedic conditions impacting on balance and/or gait performance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Participants will perform 6 tasks. We have defined a main study parameter per task Task 1: Quiet stance for 30 seconds Main study parameter: the root mean square of center of pressure velocity Task 2: Walking at self-selected comfortable speed for 3 minutes on the treadmill Main study parameter: root mean square of mediolateral center of mass position Task 3: 360° turn-in-place Main study parameter: jerkiness of the performed turn Task 4: Quiet standing in tandem stance (heel touches toe) for as long as possible Main study parameter: maximum duration (seconds) of standing in tandem stance. Task 5: Walking in tandem gait for as many steps as possible Main study parameters: maximum number of correct steps taken by the participant Task 6: Balance recovery from treadmill-induced sideways balance perturbations. Main study parameter: success of a feet-in-place recovery (i.e. the participant are able to recover their balance without taking a step). Secondary study parameter: margin of stability, defined as the distance between the body*s extrapolated center of mass (a measure that incorporates both center of mass position and velocity) and the edge of the base of support. | — |
Secondary
| Measure | Time frame |
|---|---|
| The participant*s experience with the GyBAR as a balance assisting device will be assessed via a 5-point Likert Scale. | — |
Countries
Netherlands
Outcome results
None listed