Muscle anabolism Muscle growth
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: • Female sex • Age between 18 and 35 y inclusive • BMI between 18.5 and 30 kg/m2 • Having given informed consent
Exclusion criteria
Exclusion criteria: • Intolerant to milk products • Mustard allergy • Participating in a structured (progressive) exercise program • Smoking regularly • Diagnosed GI tract disorders or diseases • Diagnosed musculoskeletal disorders • Diagnosed metabolic disorders (e.g. diabetes) • Hypertension (blood pressure above 140/90 mmHg) • Donated blood 3 months prior to test day • Pregnant • Using third generation oral contraceptives • Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories). • Chronic use of gastric acid suppressing medication • Chronic use of anti-coagulants • Recent (
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postprandial muscle protein synthesis rates (0-5h) | — |
Secondary
| Measure | Time frame |
|---|---|
| Basal muscle protein synthesis rates Plasma glucose, insulin, amino acids + corresponding peak values and (i)AUC Plasma 13C6-phe enrichments Muscle signalling pathways | — |
Countries
Netherlands