Prevalence of Lyme neuroborreliosis among patients with painful radiculopathy visiting a teaching hospital in a Lyme endemic region

Prevalence of Lyme neuroborreliosis among patients with painful radiculopathy visiting a teaching hospital in a Lyme endemic region - Lymeradiculopathy

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51614

Enrollment

500

Registered

2022-04-21

Start date

2022-06-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lyme disease

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: - All patients visiting the neurology outpatient clinic of Gelre hospitals who undergo an MRI scan for the indication of painful radiculopathy - 18 years or older - Given informed consent for participation in the study

Exclusion criteria

Exclusion criteria: - Patients who undergo an MRI scan for other reasons than radiculopathy - Patients who have radiculopathy as a residual symptom after being adequately treated for Lyme neuroborreliosis - Patients with a known other explanation for radiculopathy at time of referral, for example leptomeningeal metastasis or varicella zoster infection

Design outcomes

Primary

Measure	Time frame
The primary study parameters are the result of Borrelia serology (positive/negative) and the result of the MRI scan (yes/no nerve root compression). Patients with positive Borrelia serology and no nerve root compression will be offered a lumbar puncture to test for Lyme neuroborreliosis.	—

Secondary

Measure	Time frame
-Differences in patient characteristics and additional symptoms of patients with radiculopathy caused by Lyme neuroborreliosis versus patients with radiculopathy due to nerve root compression.	—

Countries

Netherlands

Outcome results