Muscle anabolism Muscle growth
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: * Age between 18 and 35 y inclusive * BMI between 18.5 and 30 kg/m2 * Having given informed consent
Exclusion criteria
Exclusion criteria: * Participating in a structured (progressive) exercise program * Smoking regularly * Allergy to house dust mites or crustaceans * Diagnosed GI tract disorders or diseases * Diagnosed musculoskeletal disorders * Diagnosed metabolic disorders (e.g. diabetes) * Cardiovascular disease * Hypertension (blood pressure above 140/90 mmHg) * Donated blood 3 months prior to testday * Pregnant * Amenorrhea * Using third generation oral contraceptives * Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories). * Chronic use of gastric acid suppressing medication * Chronic use of anti-coagulants
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postprandial muscle protein synthesis rates (0-6h) | — |
Secondary
| Measure | Time frame |
|---|---|
| Postprandial muscle protein synthesis rates (0-3 en 3-6h) Plasma glucose, insuline en aminozuurconcentrations + corresponding peakvalues and (i)AUC Plasma 13C6-phenylalanine enrichments | — |
Countries
Netherlands