Risk-taking behavior of healthy participants Decision-making Rist-taking behavior
Conditions
Interventions
1. Investigational product/treatment
MAXTENS 2000 TENS (formerly known as PROSTIM 2000) (MedCat B.V., Klazienaveen,
The Netherlands) used for non-invasive vagus nerve stimulation (nVNS) according
to
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: Healthy right handed participants with ages between 18 and 35 years old
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: • Age above 35 years. • Facial or ear pain. • Metal implants including pacemakers. • Pregnancy. • Personal or family history of seizure, mood, or cardiovascular disorders. • Dependence on alcohol. • Recent illicit drug use, on any pharmacological agents known to increase seizure risk. Considering our hypothesis that the nVNS will send a similar signal to the CNS that the one generated by the prolonged use of probiotics, we will exclude participants that currently include probiotics in their diet as a measure to avoid confounding factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the change in risk-taking behavior, measured using the MGT and comparing the participant*s choices during active nVNS and sham nVNS (Dantas et al., 2021). | — |
Secondary
| Measure | Time frame |
|---|---|
| Besides the calculation of participants* risk-taking behavior, their average choices of values and probabilities are also estimated. Finally, we also analyze participants* response times. | — |
Countries
Netherlands
Outcome results
None listed