Pregnancy and the human brain: a window of neuroplasticity

Pregnancy and the human brain: a window of neuroplasticity - PHB

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51565

Enrollment

250

Registered

2022-03-07

Start date

2023-04-04

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

the effects of a healthy pregnancy Healthy pregnancy Healthy pregnancy

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1. Women of age between 20 and 45 years 2. The intention to become pregnant (pregnancy group) or not (control group) in the near future 3. No neurological disorder/disease 4. No contraindications to MRI 5. No previous pregnancy beyond the first trimester

Exclusion criteria

Exclusion criteria: 1. History of neurological disorder/disease 2. Contraindications to MRI, which include metal implants, heart arrhythmia, claustrophobia, and possible early pregnancy 3. A previous pregnancy beyond the first trimester

Design outcomes

Primary

Measure	Time frame
Changes in measures of brain structure and function relative to the pre-pregnancy baseline session.	—

Secondary

Measure	Time frame
We will relate these changes in brain structure and function during pregnancy to gestational hormone levels, genetic factors, biological and lifestyle factors, contingent changes in cognitive and social-cognitive functioning and behavioral and neural indices of postpartum maternal responsiveness.	—

Countries

Netherlands

Contacts

Public ContactE.A. Hoekzema

Amsterdam UMC

e.a.hoekzema@amsterdamumc.nl020-8913704

Outcome results