allergic esophagitis Eosinophilic esophagitis
Conditions
Interventions
Subjects will be randomized into either the intervention group, in which
subjects will receive additional education in combination with more frequent
follow up and patient reminders, or the control
Sponsors
Amsterdam UMC
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Written informed consent - Male or female patient - Age >18 years - Previous diagnosis of EoE, confirmed by histopathology, with the presence of >15 eosinophilic granulocytes per high power field (hpf) in esophageal biopsies - Current maintenance treatment for EoE with a PPI or swallowed topical corticosteroids or about to start with these maintenance medications as decided during regular clinical practice
Exclusion criteria
Exclusion criteria: - Severe and clinically unstable concomitant disease that may interfere with the subject*s ability to participate in the study - Receive investigational treatment during the study - Dilation of esophagus required - Insufficient Dutch or English language skills to understand patient information leaflets
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in treatment adherence between both groups after 12 weeks, 6 months and 12 months. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Differences in self-reported treatment adherence (measured by MARS questionnaire, 8-point MMAS, BMQ, IPQ) after 12 weeks, 6 months and 12 months. - Change in clinical symptoms (measured by SDI, DSQ) after 12 weeks, 6 months and 12 months. | — |
Countries
Netherlands
Outcome results
None listed