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Minimal invasive Microwave Ablation in early stage breaST cancER, a feasibility study

Minimal invasive Microwave Ablation in early stage breaST cancER, a feasibility study - MASTER study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON51501
Enrollment
15
Registered
2023-01-19
Start date
2023-10-02
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early stage breast cancer (stage 1)

Interventions

All 15 patients will undergo ultrasound guided minimally invasive nonsurgical MWA under local anesthesia. The patient will undergo a MRI scan on the day of admission to the hospital for standard bre

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Patient age =/> 18 years old and a solid non-lobular invasive breast tumor with a size

Exclusion criteria

Exclusion criteria: Patients with more than one breast tumor, (lymph node) metastases, breast implants or neoadjuvant chemotherapy. Also patients who are pregnant or are breastfeeding cannot participate in this study.

Design outcomes

Primary

MeasureTime frame
Minimally invasive nonsurgical MWA followed by postprocedural DCE-MRI scan in patients with early stage breast cancer is a safe and effectiveness alternative for breast surgery.

Secondary

MeasureTime frame
The quality of life, cosmetic outcome in patients treated with MWA will be non-inferior to those in patients treated with standard care, where the costs will be lower and the fear for breast cancer recurrence will be equal.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)