balance instability motor control problems
Conditions
Interventions
None listed
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: For healthy controls: • In overall good health • Age: 18 - 90 years old For patients: • Adults between the age of 18 - 90 years old who have been diagnosed with a cerebellar lesion. • Patients will be invited to participate in the study within 3-12 months after their initial diagnosis.
Exclusion criteria
Exclusion criteria: For healthy controls: • History of neurological or psychiatric disorders • Taking acute or chronic psychoactive drugs • Alcoholism • History of balance problems • Pregnant women or women currently breastfeeding • A prior neuromuscular injury (regardless of source) • Incompetence to give informed consent For patients: • Unable to walk 10 metres unaided • Unable to stand freely for 10 seconds with the eyes closed • Diagnosed with polyneuropathy • Taking acute or chronic psychoactive drugs • Alcoholism • Pregnant women or women currently breastfeeding • Incompetence to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are measures of standing balance behaviour (whole body kinematics and kinetics) and evoked balance responses (probed with sensory and/or mechanical stimuli). | — |
Secondary
| Measure | Time frame |
|---|---|
| Healthy controls and cerebellar patient participants will be asked to visit the Department of Neuroscience at Erasmus at least one time for the selected experiment. During the visit, they will perform tasks specific to each experiment. The robotic balance simulator does not present significant discomfort or risk for the participants. | — |
Countries
Netherlands
Contacts
Public ContactPA Forbes
Erasmus MC, Universitair Medisch Centrum Rotterdam
Outcome results
None listed